Chicago Prostate Center http://www.prostateimplant.com/rss/news.rss <p>Young Men Have Equivalent Biochemical Outcomes Compared With Older Men After Treatment With Brachytherapy for Prostate Cancer.<br /> Burri RJ, Ho AY, Forsythe K, Cesaretti JA, Stone NN, Stock RG.</p> <p>Department of Radiation Oncology Memorial Sloan-Kettering Cancer Center, New York, New York.</p> <p><span class="caps">PURPOSE</span>: To evaluate retrospectively the biochemical outcomes of young men treated with low-dose-rate brachytherapy for prostate cancer. <span class="caps">METHODS</span> <span class="caps">AND</span> <span class="caps">MATERIALS</span>: From 1990 to 2005, 1,665 men with clinically localized prostate cancer were treated with low-dose-rate brachytherapy +/- hormone therapy (HT) +/- external beam radiotherapy and underwent &gt;/=2 years of follow-up. Patients were stratified on the basis of age: &lt;/=60 (n = 378) and &gt;60 years (n = 1,287). Biochemical failure was defined as a prostate-specific antigen (<span class="caps">PSA</span>) nadir plus 2 ng/mL. Univariate and multivariate analyses were used to determine the association of variables with freedom from biochemical failure (FFbF). <span class="caps">RESULTS</span>: Median follow-up was 68 months (range, 24-180) for men &lt;/=60 years and 66 months (range, 24-200) for men &gt;60. For the entire group, the actuarial 5- and 8-year FFbF rates were 94% and 88%, respectively. Men &lt;/=60 demonstrated similar 5- and 8-year FFbF (95% and 92%) compared with men &gt;60 (93% and 87%; p = 0.071). A larger percent of young patients presented with low-risk disease; lower clinical stage, Gleason score (GS), and pretreatment <span class="caps">PSA</span> values; were treated after 1997; did not receive any HT; and had a high biologic effective dose (<span class="caps">BED</span>) of radiation (all ps &lt;0.001). On multivariate analysis, <span class="caps">PSA</span> (p = 0.001), GS (p = 0.005), and <span class="caps">BED</span> (p &lt; 0.001) were significantly associated with FFbF, but age was not (p = 0.665). <span class="caps">CONCLUSION</span>: Young men achieve excellent 5- and 8-year biochemical control rates that are comparable to those of older men after prostate brachytherapy. Young age should not be a deterrent when considering brachytherapy as a primary treatment option for clinically localized prostate cancer. Copyright © 2009 Elsevier Inc. All rights reserved.</p> <p><span class="caps">PMID</span>: 20044216 [PubMed &#8211; as supplied by publisher]</p> Wed, 13 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/39/Young-Men-Have-Equivalent-Biochemical-Outcomes-Compared-With-Older-Men-After-Treatment-With-Brachytherapy-for-Prostate-Cancer <p>Radical retropubic prostatectomy versus brachytherapy for low-risk prostatic cancer: a prospective study</p> Tue, 12 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/38/Radical-retropubic-prostatectomy-versus-brachytherapy-for-low-risk-prostatic-cancer-a-prospective-study <p>2 Independent Studies Released on the Effectiveness of Prostate Cancer Treatment</p> Wed, 06 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/31/2-Independent-Studies-Released-on-the-Effectiveness-of-Prostate-Cancer-Treatment <p>When Cancer Strikes Three Times; Does it Ever get any Easier</p> Wed, 06 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/32/When-Cancer-Strikes-Three-Times-Does-it-Ever-get-any-Easier <p>Athletic Brothers Shocked by Common Diagnosis of Prostate Cancer.</p> Wed, 06 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/33/Athletic-Brothers-Shocked-by-Common-Diagnosis-of-Prostate-Cancer <p>Prostate Cancer Discovered in 40 Percent of Men Who Test Negative for the Disease</p> Wed, 06 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/34/Prostate-Cancer-Discovered-in-40-Percent-of-Men-Who-Test-Negative-for-the-Disease <p>Brachytherapy Prostate Cancer Treatment Eliminates Most Dreaded Side Effects</p> Wed, 06 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/35/Brachytherapy-Prostate-Cancer-Treatment-Eliminates-Most-Dreaded-Side-Effects <p>New State-of-the-art Biopsy Detects Dyer Man&#8217;s Prostate Cancer Exceptionally Early</p> Wed, 06 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/36/New-State-of-the-art-Biopsy-Detects-Dyer-Mans-Prostate-Cancer-Exceptionally-Early <p>What Happens When &#8220;Joe Construction Guy&#8221; Gets Diagnosed With Prostate Cancer</p> Wed, 06 Jan 2010 00:00:00 -0500 http://www.prostateimplant.com/news-releases/37/What-Happens-When-Joe-Construction-Guy-Gets-Diagnosed-With-Prostate-Cancer <p>Prostate cancer surgery: Minimally invasive procedures have more serious side effects, finds study</p> <p>Study finds latest surgery technology likely is overused<br /> By Shari Roan</p> <p>Tribune Newspapers</p> <p>October 14, 2009</p> More men who need prostate cancer surgery are choosing minimally invasive techniques because these surgeries typically lead to shorter hospital stays and decrease many types of complications, including pain. This type of surgery, which often includes the use of a robot, is heavily advertised. <p>Minimally invasive techniques increased from 1 percent to 40 percent of all radical prostatectomies from 2001 to 2006 and may now be as high as 75 percent of all prostate cancer surgeries.</p> <p>But here&#8217;s a detail men should know about: The most serious complications &#8212; including incontinence and erectile dysfunction &#8212; appeared more often in men who underwent minimally invasive surgery compared with traditional surgery, according to a study Tuesday in the Journal of the American Medical Association.</p> <p>Researchers compared the outcomes for men with prostate cancer who underwent a minimally invasive procedure with men who had traditional radical prostatectomy surgery. The men who had minimally invasive surgery had shorter hospital stays (two days compared with three days), were less likely to receive transfusions (2.7 percent compared with 20.8 percent) and were at lower risk of respiratory complications (4.3 percent compared to 6.6 percent).</p> <p>However, they experienced more urinary- and genital-function complications; 4.7 percent compared with 2.1 percent.</p> <p>Although minimally invasive robotic surgery may eventually offer advantages over traditional surgery for all men, there is a learning curve among surgeons using the technology, said Dr. Jim Hu, the lead author of the paper, from Brigham and Women&#8217;s Hospital in Boston.</p> <p>&#8220;There has been rapid adoption of minimally invasive radical prostatectomy, however outcomes have not been superior,&#8221; Hu said, adding that the option appeared to have been oversold.</p> <p>Studies should be performed to determine the rate of complications as more surgeons develop expertise with the technology, he said.</p> <p>In the meantime, it might behoove men who choose this option to ask about the surgeon&#8217;s experience.</p> <p>sroan@tribune.com</p> <p>Copyright © 2009, Chicago Tribune</p> Fri, 16 Oct 2009 00:00:00 -0400 http://www.prostateimplant.com/news-releases/30/Robotic-surgery-vs-open-prostatectomy